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Rob Lowe, John Stamos, Madonna, Sandra Bullock and (Credit: AP / Amy Sussman)

Rob Lowe, John Stamos, Madonna, Sandra Bullock and more. See who else made it on our hot actors and actresses over 50 list.

Hot actors and actresses over 50

Sandra Bullock, John Stamos, Brad Pitt, Sharon Stone and more: These celebrities have sailed into their 50s and beyond looking good.

Marisa Tomei

Marisa Tomei (born Dec. 4, 1964): She got
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Marisa Tomei (born Dec. 4, 1964): She got her start on the soap "As the World Turns" and the "Cosby Show" spinoff, "A Different World," then went on to win an Oscar for her performance in the 1992 comedy "My Cousin Vinny." Tomei stars in the 2015 holiday flick "Love the Coopers."

Sandra Bullock

Sandra Bullock (born July 26, 1964): The
(Credit: AP / Jordan Strauss)

Sandra Bullock (born July 26, 1964): The "Miss Congeniality" actress (who won the 2010 Oscar for her role in "The Blind Side") was named People magazine's "World's Most Beautiful Woman" for 2015.

John Stamos

John Stamos (born Aug. 19, 1963): The Dannon
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John Stamos (born Aug. 19, 1963): The Dannon Greek Yogurt guy will always be Uncle Jesse to us thanks to his many years on 1990s sitcom "Full House."

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Rob Lowe

Rob Lowe (born March 17, 1964): Most recently
(Credit: AP / Amy Sussman)

Rob Lowe (born March 17, 1964): Most recently finding success on "Parks and Recreation," past hits have included "The Outsiders" and "St. Elmo's Fire."

Brad Pitt

Brad Pitt (born Dec. 18, 1963): Mr. Angelina
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Brad Pitt (born Dec. 18, 1963): Mr. Angelina Jolie made his mark in "Thelma & Louise" as a hot drifter cowboy in 1991.

David Duchovny

David Duchovny (born Aug. 7, 1960): The actor
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David Duchovny (born Aug. 7, 1960): The actor has been a regular in our living rooms from the sci-fi hit "The X-Files" (1993-2002) to "Californication."

Vanessa L. Williams

Vanessa L. Williams (born March 18, 1963): The
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Vanessa L. Williams (born March 18, 1963): The onetime Miss America winner has had numerous TV roles from "Ugly Betty" to "666 Park Avenue."

Valerie Bertinelli

Valerie Bertinelli (born April 23, 1960): We first
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Valerie Bertinelli (born April 23, 1960): We first knew her as young Barbara Cooper on "One Day at a Time" in the 1970s and '80s, and now she stars in TV Land's "Hot in Cleveland."

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Liam Neeson

Liam Neeson (born June 7, 1952): The Irish
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Liam Neeson (born June 7, 1952): The Irish actor has reinvented himself as a box office badass in films including "Taken" and "Non-Stop."

Angela Bassett

Angela Bassett (born Aug. 16, 1958): Best known
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Angela Bassett (born Aug. 16, 1958): Best known for playing Anna Mae Bullock, aka Tina Turner, in 1992's "What's Love Got to Do With It?"

Daniel Day-Lewis

Daniel Day-Lewis (born April 29, 1957): The chameleon-like
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Daniel Day-Lewis (born April 29, 1957): The chameleon-like Oscar winner has transformed himself for movies including "Lincoln" and "There Will Be Blood."

Gina Gershon

Gina Gershon (born June 10, 1962): She'll always
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Gina Gershon (born June 10, 1962): She'll always be Cristal Connors ("Showgirls") to us.

Viggo Mortensen

Viggo Mortensen (born Oct. 20, 1958): The actor
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Viggo Mortensen (born Oct. 20, 1958): The actor has worked with top directors from Peter Jackson ("The Lord of the Rings" trilogy) to David Cronenberg ("A History of Violence," "Eastern Promises").

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Olivia Newton John

Olivia Newton John (born Sept. 6, 1948): The
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Olivia Newton John (born Sept. 6, 1948): The actress and singer brought both talents to 1978's "Grease" and 1980's "Xanadu."

Jane Leeves

Jane Leeves (born April 18, 1961): Best known
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Jane Leeves (born April 18, 1961): Best known for playing Daphne on the Emmy Award-winning sitcom "Fraiser," the actress has also had success on "Hot in Cleveland."

John Schneider

John Schneider (born April 8, 1960): Hunky Bo
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John Schneider (born April 8, 1960): Hunky Bo Duke on "Dukes of Hazzard" went on to play Superman's dad on "Smallville" (2001-2011).

Raquel Welch

Raquel Welch (born Sept. 5, 1940): Who can
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Raquel Welch (born Sept. 5, 1940): Who can forget that bikini in 1966's "One Million Years B.C."?

Giancarlo Esposito

Giancarlo Esposito (born April 26, 1958): He's covered
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Giancarlo Esposito (born April 26, 1958): He's covered everything from righteous (Buggin' Out in "Do the Right Thing") to sinister (Tom Neville in "Revolution").

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Meryl Streep

Meryl Streep (born June 22, 1949): The multiple
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Meryl Streep (born June 22, 1949): The multiple Oscar winner has earned statues for her roles in "The Iron Lady" and "Kramer vs. Kramer."

Kim Bassinger

Kim Bassinger (born Dec. 8, 1953): She won
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Kim Bassinger (born Dec. 8, 1953): She won an Oscar for her role in "LA Confidential" in 1998.

Hugh Grant

Hugh Grant (born Sept. 9, 1960): The actor
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Hugh Grant (born Sept. 9, 1960): The actor has brought his British charms to romantic comedies including "About a Boy" and "Bridget Jones' Diary."

Julianne Moore

Julianne Moore (born Dec. 3, 1960) She has
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Julianne Moore (born Dec. 3, 1960) She has had varied roles on television (on "As The World Turns," "30 Rock") and film ("Boogie Nights," "Far From Heaven").

Dylan McDermott

Dylan McDermott (born Oct. 26, 1961): Defining TV
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Dylan McDermott (born Oct. 26, 1961): Defining TV roles include Bobby on "The Practice" and Ben on "American Horror Story."

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Sharon Stone

Sharon Stone (born March 10, 1958): Best known
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Sharon Stone (born March 10, 1958): Best known for her leading role in the 1992 thriller "Basic Instinct."

Ken Watanabe

Ken Watanabe (Born Oct. 21, 1959): Best known
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Ken Watanabe (Born Oct. 21, 1959): Best known as Saito in "Inception."

Demi Moore

Demi Moore (born Nov. 11, 1962): The Brat
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Demi Moore (born Nov. 11, 1962): The Brat Pack member grew up in "About Last Night" and "St. Elmo's Fire" and starred opposite Patrick Swayze in "Ghost."

Lance Reddick

Lance Reddick (born Dec. 31, 1962): Best known
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Lance Reddick (born Dec. 31, 1962): Best known for playing Cedric Daniels in "The Wire" and, more recently, Phillip Broyles on "Fringe."

Emma Thompson

Emma Thompson (born April 15, 1959): Her roles

Emma Thompson (born April 15, 1959): Her roles have included Nanny McPhee, Sybil Trelawney in the Harry Potter films and Elinor Dashwood in "Sense and Sensibility."

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George Clooney

George Clooney (born May 6, 1961): Knows for
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George Clooney (born May 6, 1961): Knows for his roles "ER" and the "Ocean's Eleven" films, the actor received an Oscar nomination for his leading role in "The Descendants."

Susan Sarandon

Susan Sarandon (born Oct 4. 1946): Best known
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Susan Sarandon (born Oct 4. 1946): Best known for her roles in 1977's "Rocky Horror Picture Show" and 1991's "Thelma and Louise."

Antonio Banderas

Antonio Banderas (born Aug. 10, 1960): The Spanish-born
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Antonio Banderas (born Aug. 10, 1960): The Spanish-born actor has starred in Pedro Almodovar films ("The Skin I Live In," "Labyrinth of Passion") to Hollywood fare ("Zorro").

Michelle Pfeiffer

Michelle Pfeiffer (born April 29, 1958): Known for
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Michelle Pfeiffer (born April 29, 1958): Known for her role as Catwoman in 1992's "Batman Returns."

Johnny Depp

Johnny Depp (born June 9, 1963): Best known
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Johnny Depp (born June 9, 1963): Best known for playing eccentric characters including vampire Barnabus Collins in "Dark Shadows," Captain Jack Sparrow in the "Pirates of the Caribbean" series, Willy Wonka in 2005's "Charlie and the Chocolate Factory" and the title role in the 1990's "Edward Scissorhands."

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Holly Hunter

Holly Hunter (born March 20, 1958): Best known
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Holly Hunter (born March 20, 1958): Best known for her role in 1993's "The Piano."

Pierce Brosnan

Pierce Brosnan (born May 16, 1953): The Irish
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Pierce Brosnan (born May 16, 1953): The Irish actor is equal parts "Remington Steele" and James Bond.

Helen Mirren

Helen Mirren (born July 26, 1945): The Dame's
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Helen Mirren (born July 26, 1945): The Dame's decades-spanning career includes her Oscar-winning portrayal of Queen Elizabeth in 2006's "The Queen."

John Slattery

John Slattery (born Aug. 13, 1962): The
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John Slattery (born Aug. 13, 1962): The "Mad Men" actor also gave a notable turn as Victor Lang on "Desperate Housewives."

Kelly Preston

Kelly Preston (born Oct. 13, 1962): Best known
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Kelly Preston (born Oct. 13, 1962): Best known as a former model and actress in the 1996 film, "Jerry Maguire."

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Jennifer Tilly

Jennifer Tilly (born Sept. 16, 1958): Best known
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Jennifer Tilly (born Sept. 16, 1958): Best known for her roles in the "Chucky" horror films.

Lou Diamond Phillips

Lou Diamond Phillips (born Feb. 17, 1962): Probably
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Lou Diamond Phillips (born Feb. 17, 1962): Probably best known for his role in the 1987 film "La Bamba."

Madonna

Madonna (Born Aug. 16, 1958): The singer has
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Madonna (Born Aug. 16, 1958): The singer has a number of acting roles on her resume, including "Desperately Seeking Susan" (1985), "Dick Tracy" (1990), "A League of Their Own" (1992) and "Evita" (1996).

Ellen Degeneres

Ellen Degeneres (born Jan. 26, 1958): The comedian
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Ellen Degeneres (born Jan. 26, 1958): The comedian and talk show host has acted in sitcoms ("Ellen," from 1994-98) and on film (1996's "Mr. Wrong).

Kevin Costner

Kevin Costner (born Jan. 18, 1955): Best known
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Kevin Costner (born Jan. 18, 1955): Best known for directing and starring in 1990's "Dances with Wolves."

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Rene Russo

Rene Russo (born Feb. 17, 1954): Best known
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Rene Russo (born Feb. 17, 1954): Best known for her roles in "Lethal Weapon" 3 and 4.

Joan Allen

Joan Allen (born Aug. 20, 1956): Best known
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Joan Allen (born Aug. 20, 1956): Best known as the grounded Pam Landy in the "Bourne" series.

Richard Gere

Richard Gere (born Aug. 31, 1949): The
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Richard Gere (born Aug. 31, 1949): The "American Gigolo" and "Breathless" star has kept relevant in later films such as 2012's "Arbitrage."

Jaclyn Smith

Jaclyn Smith (born Oct. 26, 1945): Best known
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Jaclyn Smith (born Oct. 26, 1945): Best known as one of the original "Charlie's Angels."

Jane Seymour

Jane Seymour (born Feb. 15, 1951): Best known
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Jane Seymour (born Feb. 15, 1951): Best known for her lead role in the 1993 TV series "Dr. Quinn, Medicine Woman."

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Rebecca De Mornay

Rebecca De Mornay (born Aug. 29, 1959): Best
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Rebecca De Mornay (born Aug. 29, 1959): Best known for her role opposite Tom Cruise in 1993's "Risky Business."

Colin Firth

Colin Firth (born Sept. 10, 1960): Best known
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Colin Firth (born Sept. 10, 1960): Best known for his Academy Award-winning role in the 2011 film, "The Kings Speech."

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