Given the track record of "Pirates of the Caribbean" producer Jerry Bruckheimer, director Gore Verbinski and studio Walt Disney Pictures, their new collaboration, "The Lone Ranger," may well leave all previous Westerns behind in a cloud of dust and a hearty "Hi-yo, Silver!"
Here are the genre's 10 highest-grossing movies -- adjusted for inflation, or else a money-losing flop like "Cowboys & Aliens" comes in at No. 8!
1. "Butch Cassidy and the Sundance Kid" $560,229,400
The Paul Newman-Robert Redford 1969 buddy classic that made the latter a star won Oscars for original screenplay (William Goldman), cinematography (Conrad L. Hall), score (Burt Bacharach) and song (Bacharach and Hal David's "Raindrops Keep Fallin' on My Head").
2. "Blazing Saddles" $502,026,500
The 1974 Mel Brooks comedy-Western starring Cleavon Little and Gene Wilder is considered one of cinema's funniest films.
3. "Duel in the Sun" $405,102,000
King Vidor's 1946 Technicolor tale of a half-American Indian (Jennifer Jones) facing prejudice and forbidden love was a scandalous hit.
4. "Dances with Wolves" $346,972,400
Told from the cultural perspective of the Lakota people, director-star Kevin Costner's 1990 epic took seven Academy Awards, including best picture, director, cinematography and original score.
5. "Shane" $272,635,000
No. 3 on the American Film Institute's list of greatest Westerns, behind John Ford's "The Searchers" (1956) and Fred Zinnemann's "High Noon" (1952), is George Stevens' 1953 classic about a gunslinger and a family in the changing frontier.
6. "Little Big Man" $184,064,401
A 121-year-old's (Dustin Hoffman) memories satirize and comment on the Old West in this 1970 Western.
7. "True Grit" $171,243,005
The Coen brothers' 2010 remake of the 1969 John Wayne film earned Hailee Steinfeld a supporting-actress Oscar nomination for her first film.
8. "The Good, The Bad and the Ugly" $170,261,707
Clint Eastwood. Sergio Leone. Climactic 1966 spaghetti Western of "The Man With No Name" trilogy.
9. "Unforgiven" $163,059,604
Director-star Eastwood's poignant 1992 bookend to the above won four Oscars, including best picture, director and supporting actor (Gene Hackman).
10. "Django Unchained" $162,805,434
From 2012: Quentin Tarantino goes West.