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In this Nov. 15, 1988, file photo, television
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In this Nov. 15, 1988, file photo, television talk-show host Oprah Winfrey shows off her new figure during taping of her show in Chicago after she lost 67 pounds following a liquid diet and exercise. (Credit: AP)

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'The Oprah Winfrey Show' memorable moments and guests

For 25 years, Oprah Winfrey reigned as the queen of talk shows. Take a look at some of her show's biggest moments.

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