- Cabot, John
- Calatrava, Santiago
- Caldwell, Erskine
- Caldwell, Sarah
- Calvin, John
- Calvino, Italo
- Cameron, Richard
- Campbell, Alexander
- Campbell, Robert
- Campbell, William
- Camus, Albert
- Canetti, Elias
- Capa, Robert
- Capone, Al
- Capote, Truman
- Cardin, Pierre
- Carey, Peter
- Carlyle, Thomas
- Carmichael, Stokely
- Carnegie, Andrew
- Carroll, Charles
- Carroll, James
- Carroll, John
- Cartier-Bresson, Henri
- Caruso, Enrico
- Carver, George Washington
- Carver, Raymond
- Cassatt, Mary
- Cassini, Oleg
- Cellini, Benvenuto
- Chagall, Marc
- Chamberlain, John
- Chambers, Robert
- Chambers, Whittaker
- Chanel, Coco
- Charest, Jean
- Chase, Samuel
- Chaucer, Geoffrey
- Cheever, John
- Chen Yi
- Chicago, Judy
- Child, Julia
- Christian, Charlie
- Churchill, Winston Leonard Spencer
- Clark, Joe
- Clark, Ramsey
- Clay, Henry
- Cleaver, Eldridge
- Cleland, John
- Cliburn, Van
- Close, Chuck
- Clurman, Harold
- Cobb, Ty
- Cody, John
- Cohen, Stanley
- Collins, Michael
- Collins, Wilkie
- Collins, William
- Colt, Samuel
- Comaneci, Nadia
- Conkling, Roscoe
- Connally, John
- Connelly, Marc
- Constable, John
- Copland, Aaron
- Corelli, Arcangelo
- Corelli, Franco
- Cornell, Joseph
- Courbet, Gustave
- Crandall, Prudence
- Crane, Hart
- Crockett, Davy
- Cromwell, Oliver
- Cronkite, Walter
- Cruz, Celia
- Cunningham, Imogen
- Cunningham, Merce