Police charged James Fontana, 42, with assault and criminal possession of a weapon after officers caught him running from Jugs and Stroker's Bar at 1828 Sunrise Hwy. at 1:50 a.m.
Police said Fontana swung the bottle at the man's face, deeply cutting his nose.
The victim, 23, was taken by private vehicle to a hospital, where several stitches were required to close the wound, police said.
Fontana was scheduled to be arraigned Sunday at First District Court in Hempstead.