One man was killed and five firefighters who were early on the scene of an East Farmingdale house fire were taken to the hospital Wednesday afternoon, police and a fire official said.

The man, who wasn't immediately identified, was taken to Nassau University Medical Center in East Meadow, where he was pronounced dead. He was the only person in the home at Melville Road and Alexander Avenue at the time, Suffolk police said.

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Four of the firefighters were taken to St. Joseph Hospital in Bethpage, with minor burns and injuries, and the fifth was taken to the medical center, the official said. None of their injuries was life-threatening, said Joseph Scura, spokesman for the East Farmingdale Fire Department.

The firefighter at NUMC had been evaluated "to determine if hyperbaric treatment will be needed," said Shelley Lotenberg, medical center spokeswoman.

Five fire departments responded to the blaze, and they brought it under control by about 4:30 p.m., Scura said.

Responding were firefighters from East Farmingdale, Farmingdale, South Farmingdale, Melville and Bethpage, he said. The call came in about 3:21 p.m., he said.

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The cause of the blaze was unknown, and the Suffolk County police arson squad was investigating, Scura said, which is required when injuries have occurred.