A motorcyclist was seriously injured in a crash Monday morning on Commack Road in Brentwood, police said.

A southbound Ford Focus “crossed into the northbound lane and struck a southbound motorcycle,” north of Spur Drive North, at about 10:20 a.m., Suffolk County police said.

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The motorcyclist, identified only as a male, was taken to a hospital with a serious leg injury, police said. The driver of the Focus, identified only as a female, was taken to a hospital with minor injuries, police said.

Commack Road was temporarily closed during the subsequent investigation.