Project title: Targeting Loop Dynamics in Beta I / Beta III Isotype Tubulin: The Application of In Silico Techniques in Combating Chemotherapy Drug Resistance
Description: For his project, Ruoyi Jiang obtained a federal permit to use a government-owned supercomputer in
simulating the effects of the drug Taxol on cancerous tumors. Results allowed Jiang to predict long-range effects of drug binding on protein structure. Results also suggest that such simulations could contribute to development of new drugs for treatment of cancers resistant to older pharmaceuticals.