Starting Wednesday, drivers on Sunrise Highway in the Town of Babylon should expect some lane shifts and closures, weather permitting, during off-peak hours.

From 10 a.m. to 3 p.m., a single eastbound and/or westbound Sunrise Highway travel lane is to be closed near Route 110 in the town, the state Department of Transportation said.

Likewise, from 10 p.m. to 6 a.m., one and/or two travel lanes may be closed in one or both directions, the DOT said.

This is to allow for constructing “the approaches and support for the temporary bridge over NY 27 which will keep traffic flowing on NY 110 while the old, deteriorated bridge is being replaced,” said DOT spokeswoman Eileen Peters.

The Monday through Friday work is expected to last through May.

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While most of the time at least one lane in each direction will remain open, occasionally at night the highway will be briefly closed completely, the DOT said.

In those cases, if needed, drivers will be directed to a short detour around the construction, then back to the highway, the DOT said.

Drivers are advised to take alternate routes or be prepared for delays.