One or more lucky Powerball ticket holders might be in for a sweet ’16.

The year’s first drawing in the multistate lottery was held Saturday night. The numbers were 5, 6, 15, 29, 42. Powerball: 10. Power Play: 2.

After previous drawings came up without a jackpot winner, the grand prize stood at $334 million, or a lump sum of $205 million.

Before Saturday night’s drawing, the drawn tickets have lacked a match for the key Powerball, pushing up the jackpot’s value.

Robin Jones was at what she considers her lucky 7-Eleven in Glen Cove with her two grandchildren Saturday morning preparing to play.

“I always play, to be honest,” said Jones, 46, of Glen Cove. “Three times this year I hit big. They know me very well here.”

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Jones has a strategy: She said she’s had luck playing numbers from her license plate and family members’ license plates. She hopes those numbers come through for her again.

“It’s up there,” she said of the jackpot.

Abdul Qureshi, 58, manager of Oak Neck Wine and Liquors in West Islip, said when the jackpot grows, many of the store’s regular customers play. But they usually wait until later in the afternoon, he said.

As for Qureshi, he always plays when the jackpot reaches $200 million or more, he said. He’s won $7 and $12 in the past, but has never hit any big money. Still, the Babylon resident said he only ever spends $5 or $6 on the games, and only when the jackpot is high.

If he wins, Qureshi didn’t hesitate to say what he plans to do with the money.

“First I will go back to my country and see my family,” he said. “And then relax.” Qureshi is from Mumbai, India, where he still has brothers and sisters.

If he won the $334 million jackpot Saturday night, he admitted he probably wouldn’t work in the liquor store anymore.

But, if he hits it big: “Maybe I’ll buy this place,” he said.

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The highest jackpot recorded in the past decade topped $590 million, awarded as almost $371 million in a cash lump sum to a Florida woman in 2013.

Last year, three winners in North Carolina, Puerto Rico and Texas split a $564 million jackpot as $381.1 million cash in February, and a Michigan woman took home a $310 million prize as $197.5 million cash in October.

There was also a Powerball grand-prize winner from Tennessee in November, though that person took home a more modest $144.1 million as $90 million in cash. Saturday’s $334 million jackpot is the 12th largest in the game’s history, according to The Associated Press.

The chances of winning are about 1 in 292 million.

With Candice Ruud and Will James