Donald Trump attacked presidential race rivals from both parties Sunday, calling Ted Cruz a “maniac” and saying Hillary Clinton has “killed hundreds of thousands” with her policies as secretary of state.

The Manhattan real estate developer said on “Fox News Sunday” that Cruz, the senator from Texas who surged ahead of him in a new Iowa poll, isn’t qualified to be president because he doesn’t have the “right temperament.”

“You look at the way he’s dealt with the Senate, where he goes in there frankly like a little bit of maniac,” Trump said. “You’re never going to get things done that way. . . . You can’t walk into the Senate and scream and call people liars and not be able to cajole and get along with people.”

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Trump, the front-runner in national polls for the Republican 2016 nomination, targeted the Democratic Party’s leading candidate in the same interview with host Chris Wallace.

“She’s got no strength, she’s got no stamina, everything she does is like theatrical,” Trump said of Clinton, before mocking her recent statement about him that “I think he’s dangerous.”

“I’m dangerous?,” Trump said. “She’s the one that caused all these problems, with her stupid policies. . . . She’s killed hundreds of thousands of people with her stupidity.”

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Without details, Trump cited the former secretary of state’s policies on Libya, Syria and Egypt, which he charged left the Middle East region a “total disaster.”

Wallace had tried to discuss Trump’s high unfavorable ratings among women, black and Hispanic voters in a recent poll, but the billionaire businessman cut him off.

Representatives of Cruz and Clinton’s campaigns yesterday did not respond to requests for comment on Trump’s criticisms.

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Cruz, however, on Sunday tweeted a Fox News poll that showed the Texan lawmaker leading by 7 percentage points over Trump for the GOP nod among likely caucusgoers in early-voting Iowa. A Des Moines Register poll released Saturday showed Cruz ahead of Trump by 10 points in Iowa.

Clinton said Thursday on NBC’s “Late Night with Seth Myers” that Trump’s rhetoric, including a proposal to ban Muslims from entering the United States amid recent terrors attacks, “is not only shameful and wrong, it’s dangerous.”