For the third time this week, in a third borough, a city police officer has shot a suspect, the NYPD said.

The latest shooting occurred just after 4 a.m. Friday, when a sergeant, assigned to a 70th Precinct anti-crime patrol, encountered a man with a knife while investigating a theft of tires from a car on East 19th Street in Brooklyn, police said.

The sergeant, who was not identified, fired once -- striking the man.

The man fled; as of 5 p.m., he had not been apprehended, police said.

One of the two earlier police-involved shootings took place Tuesday night in East Harlem. The other took place during a domestic dispute in the Bronx on Wednesday. In that case, a man was shot and killed. In each shooting, the suspect had pointed a gun at police, officials said.

Police said Friday's shooting began when the sergeant, on plainclothes patrol in an unmarked car, encountered two men stealing tires from a 2015 Honda Fit on East 19th Street near Glenwood Road in Flatbush. When the sergeant went to investigate, police said, the men fled in two waiting vehicles.

advertisement | advertise on newsday

The sergeant then notified two plainclothes officers of the direction in which the men fled. With the sergeant still at the initial scene, another vehicle, with two men inside, came to the location to retrieve items -- and when the sergeant identified himself, the two men tried to drive away, police said.

Their vehicle struck a parked car, police said. When the sergeant attempted to "engage" the men after he stopped their vehicle, police said, they ignored "multiple orders" to remain in the auto and one man menaced the officer with a knife. After that man ignored "multiple orders" to drop the weapon, the sergeant fired a shot that struck the man, police said.

The man then fled.

A 26-year-old passenger in the car was arrested. He was not hurt, police said. Charges are pending.

The sergeant was taken to Kings County Hospital for treatment of tinnitus.