Jose Reyes did two notable things during his first-inning at-bat on Saturday night: He picked up his 2,000th hit and injured a muscle in his left rib cage.

Reyes was scratched from Sunday’s lineup about 90 minutes before game time because the effects of the injury — the Mets called it “tightness” — got worse overnight.

Reyes said he felt it on a pair of checked swings during his first at-bat Saturday night, but he stayed in the game and went 3-for-4 with a walk and two RBIs, lifting his average above .200 (.205) for the first time this season.

Reyes said he tried to talk his way back into the lineup, but Terry Collins, fearful of the tightness becoming something more serious, would not relent. The Mets have an off-day Monday, which gives Reyes an extra day to heal.

“I came in today with the attitude that I’m going to play,” said Reyes, who went on the disabled list last July 30 with the same injury and didn’t return until Aug. 13. “They won’t let me. I went back and forth with Terry a couple of times to try to leave me in the lineup. He said no. He didn’t want to take a risk. You know what’s happened with some players here.”

Matt Reynolds replaced Reyes at short and went 1-for-4 with a solo home run in the Mets’ 12-5 loss to the Angels. Wilmer Flores moved from sixth to second in the order and went 2-for-4.

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Extra bases

Travis d’Arnaud (bruised right wrist) went 3-for-5 with two doubles and an RBI in a rehab game for Triple-A Las Vegas . . . Angels shortstop Andrelton Simmons, who went 2-for-6 with a double and three-run home run, is a .333 hitter (81-for-243) against the Mets . . . Mike Trout finished the three-game series 4-for-8 with a home run and four RBIs. The Mets walked him five times, twice intentionally.