CHICAGO - Luis Severino will make his long-anticipated big-league debut Wednesday night against the Red Sox at the Stadium, Joe Girardi said.

Speaking before Saturday night's game, Girardi said Masahiro Tanaka will start the first game of the series Tuesday night, followed by Severino and CC Sabathia. As of now, Severino is taking the rotation spot of Michael Pineda, put on the disabled list Thursday with a strained flexor muscle in his right forearm.

Severino, a 21-year-old righthander, has had Yankees fans salivating for more than a year, and the hype has reached a fever pitch this season.

After a terrific stretch with Double-A Trenton, Severino was even better with Triple-A Scranton/Wilkes-Barre, going 7-0 with a 1.91 ERA in 11 starts. In his most recent game, he allowed one hit and struck out 10 in six shutout innings against Lehigh Valley on Wednesday.

Severino already has thrown 991/3 innings this season but will not have an innings limit down the stretch, general manager Brian Cashman said. That means that as long as Severino produces, expect him to stay with the club.

"We prepared in the front end of this thing that if we needed him, we needed to make sure that he was available to provide what we needed, so there isn't an innings limit on him," Cashman said. "He's good to go."

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McCann OK

Brian McCann did not start for the second straight game, replaced by John Ryan Murphy, but he pinch hit for Murphy in the sixth inning Saturday night and homered in the ninth. "My original thought was I was going to play Brian Friday and Sunday," Girardi said. "But when we had the long two days in Texas [Wednesday and Thursday], I said, 'no.' And I'm not going to play him tonight and then again tomorrow [a day game]. So it just works better, especially with the lefty [John Danks] tonight and the righty [Jeff Samardzija] tomorrow."