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OCT. 21, 1998: STIFLES PADRES IN WORLD SERIES-CLINCHER (Credit: Newsday / Audrey C. Tiernan)

OCT. 21, 1998: STIFLES PADRES IN WORLD SERIES-CLINCHER
Pettitte completed a dominant World Series victory for the Yankees over the Padres by throwing 7 1/3 shutout innings in a 3-0 Game 4 win that closed out the sweep.

The career of Andy Pettitte

Andy Pettitte won five World Series titles and 240 games in his major league career (203 of them with the Yankees) before retiring in 2010 and returning in 2012. Here's a look at some of the most significant moments in a memorable career.

APRIL 29, 1995: MLB DEBUT Andy Pettitte made
(Credit: AP)

APRIL 29, 1995: MLB DEBUT
Andy Pettitte made his debut in relief of Melido Perez, who earned the win against the Kansas City Royals. It wasn't exactly a promising start -- he gave up three hits and two runs in 2/3 of an inning. But Pettitte would go on to post a 12-9 record with a 4.17 ERA and finish third in the AL Rookie of the Year voting behind the Twins’ Marty Cordova and Garrett Anderson of the Angels.

APRIL 9, 1996: HOME OPENER IN THE SNOW
(Credit: Newsday / Paul J. Bereswill)

APRIL 9, 1996: HOME OPENER IN THE SNOW
The Yankees' dynasty began in 1996, but their first home game that year was played in less-than-desirable weather conditions: The Yankees faced the Royals in a light but steady snowfall. The elements didn’t bother Pettitte as he pitched 6 1/3 innings while giving up six hits and two earned runs, striking out six in a 7-3 win.

JULY 1996: MAKES FIRST ALL-STAR TEAM After going
(Credit: Newsday / Bill Davis)

JULY 1996: MAKES FIRST ALL-STAR TEAM
After going 13-4 with a 3.81 ERA in his first 19 starts, Pettitte was named to his first All-Star team in 1996. He didn’t appear in the game, though, as the National League All-Stars won, 6-0.

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OCT. 24, 1996: OUTDUELS SMOLTZ IN WORLD SERIES
(Credit: AP)

OCT. 24, 1996: OUTDUELS SMOLTZ IN WORLD SERIES GAME 5
After taking a beating in Game 1 of the 1996 World Series against the Atlanta Braves, Pettitte returned to the hill in a crucial Game 5 with the series tied 2-2. Pettitte responded with a gem, going 8 1/3 innings and allowing no runs in a 1-0 win over John Smoltz and the Braves. The Yankees would go on to win their first championship in 18 years in Game 6 at Yankee Stadium.

OCT. 21, 1998: STIFLES PADRES IN WORLD SERIES-CLINCHER
(Credit: Newsday / Audrey C. Tiernan)

OCT. 21, 1998: STIFLES PADRES IN WORLD SERIES-CLINCHER
Pettitte completed a dominant World Series victory for the Yankees over the Padres by throwing 7 1/3 shutout innings in a 3-0 Game 4 win that closed out the sweep.

OCT. 26, 2000: OUTDUELS LEITER IN SUBWAY SERIES
(Credit: Getty Images)

OCT. 26, 2000: OUTDUELS LEITER IN SUBWAY SERIES GAME 5
In a classic pitchers' duel, Pettitte battles Mets starter Al Leiter in Game 5 of the 2000 World Series at Shea Stadium. After committing a second-inning error that helped the Mets' only two runs score, Pettitte shut out the Mets the rest of the way and the Yankees went on to win the game 4-2 to win their fourth title in five years.

DEC. 16, 2003: SIGNS WITH HOUSTON Yankee fans
(Credit: AP)

DEC. 16, 2003: SIGNS WITH HOUSTON
Yankee fans were shocked when Pettitte decided to sign a three-year, $31.4 million dollar deal with the Houston Astros. Good friend Roger Clemens later came out of retirement to join Pettitte with the hometown Astros.

OCT. 2005: PITCHES ASTROS TO FIRST WORLD SERIES
(Credit: AP)

OCT. 2005: PITCHES ASTROS TO FIRST WORLD SERIES
Pettitte went 17-9 with a career-best 2.39 ERA in 2005, leading the Astros to their first-ever World Series. Pettitte got a no-decision in his Game 1 start, but the Astros were swept by the White Sox.

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DEC. 8, 2006: ANDY RETURNS TO THE BRONX
(Credit: Newsday / Alejandra Villa)

DEC. 8, 2006: ANDY RETURNS TO THE BRONX
Pettitte's career came full circle as he signed a one-year, $16 million-dollar deal to return to the Bronx. In his first season back in pinstripes, he won 15 games.

SEPT. 19, 2007: 200th WIN Wins his 200th
(Credit: Newsday / Paul J. Bereswill)

SEPT. 19, 2007: 200th WIN
Wins his 200th career game against Baltimore. Pettitte throws 7 2/3 innings, allowing one run and striking out four. Pettitte will end his career with more wins against the Orioles (27) than any other team.

FEB. 4, 2008: TESTIFIES BEFORE CONGRESS In a
(Credit: MCT)

FEB. 4, 2008: TESTIFIES BEFORE CONGRESS
In a hearing for a Congressional panel on performance-enhancing drug use in baseball, Pettitte swears under oath that longtime friend and former Houston and Yankees teammate Roger Clemens used HGH in 1999 or 2000.

FEB. 18, 2008: APOLOGIZES FOR HGH USE In
(Credit: Newday / Audrey C. Tiernan)

FEB. 18, 2008: APOLOGIZES FOR HGH USE
In a press conference on the first day of spring training, Pettitte apologized to fans and teammates for using human growth hormone (HGH). During the offseason, Pettitte was named in the Mitchell Report for using HGH, which he received from trainer Brian McNamee.

SEPT. 21, 2008: WINS LAST GAME AT YANKEE
(Credit: Newsday / Paul J. Bereswill)

SEPT. 21, 2008: WINS LAST GAME AT YANKEE STADIUM
In the final game ever at the original Yankee Stadium, Pettitte got the start. He recorded his 2,000th career strikeout in the second inning and threw five innings to earn the victory as the Yankees defeated the Baltimore Orioles, 7-3.

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OCT. 2009: ANDY CLOSES OUT ALL THREE PLAYOFF
(Credit: AP)

OCT. 2009: ANDY CLOSES OUT ALL THREE PLAYOFF SERIES On their way to their 27th world championship, the Yankees called on Pettitte in all three series-clinching games. He won all three, defeating the Twins, Angels and Phillies. Overall, Pettitte had an MLB-record six postseason-series clinching wins, along with 19 postseason wins -- also a record.

JULY 12, 2010: FINAL ALL-STAR APPEARANCE Pettitte began
(Credit: AP)

JULY 12, 2010: FINAL ALL-STAR APPEARANCE
Pettitte began his final season in remarkable fashion at age 38. He was 11-2 with a 2.70 ERA at the All-Star break and was named to Midsummer Classic for the first time since 2001. Injuries slowed the lefty down in the second half, but he went 1-1 with a 2.57 ERA in the 2010 postseason.

FEB. 4, 2011: PETTITTE RETIRES After 16 seasons
(Credit: Craig Ruttle)

FEB. 4, 2011: PETTITTE RETIRES
After 16 seasons in the Majors, includng 13 with the Yankees, Pettitte retires to be with his family in Texas. He retired with 240 career wins (203 as a Yankee) and the most postseason victories (19) in Major League Baseball history.

MARCH 16, 2012: THE COMEBACK After a year
(Credit: Newsday/J. Conrad Williams Jr.)

MARCH 16, 2012: THE COMEBACK
After a year away from the game, Pettitte comes out of retirement and signs a one-year, $2.5 million minor-league deal with the Yankees.

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