The 12-5 matchup is usually the first place people look for the upset. You may not be disappointed.

No.12 UTEP vs. No.5 Butler

Why? Because Butler struggles against teams with power inside games. And Utep has one with 69, 275-pound Derek Caracter. Caracter, a Louisville transfer, is averaging 13.8 points per game on 56 percent shooting. If Caracter gets going early, look out. UTEP guard Randy Culpepper is a scoring machine. Caracter could open things up for him with some early production.

No.13 Murray State vs. No.4 Vanderbilt

Why? Because Murray State has five players averaging 10 or more points per game and a sixth who is averaging 9.5 points per game. Depth has been the name of the game for the Racers. But they need to find a go-to-guy. If they do, Vanderbilt, not exactly the fastest team in the country, could struggle. 

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No.12 Cornell vs. No.5 Temple

Why? Because Cornell was underseeded. The Big Red probably should've been a seventh seed. Considering how well they played against Kansas and some of their non-conference wins (St. John's, Drexel, Vermont), Cornell probably figured it was going to get a favorable seed. But don't be fooled, Temple plays excellent defense. The Owls are fourth in the country in scoring defense (56.8) and could fluster the Big Red on the perimeter. 

No.11 Old Dominion vs. No.6 Notre Dame

Why? Because Old Dominion won at Georgetown and destroyed a pretty good Charlotte team during the regular season. The Monarchs played great basketball down the stretch in winning the CAA tournament. Notre Dame expended a lot of energy getting itself into the tournament. WIll the Irish be too drained mentally and physically to put up a fight?  

For anyone wondering why No.13 Siena vs. No.4 Purdue isn't on this list, it's simple. The absence of Robbie Hummel weakens Purdue considerably. Purdue was down, 37-11, at the half during its loss to Minnesota in the Big Ten semifinal. Sure, the Boilermakers won three of their last four games, but those victories came against Indiana, Penn State and Northwestern. Purdue got crushed by Michigan State, 58-44, prior to those three wins. This won't be considered an upset.