Colin Kaepernick passed for 243 yards and two touchdowns in his first career start in place of the injured Alex Smith, and the 49ers routed the Bears, 32-7, Monday night in San Francisco.

Kaepernick threw TD passes to Vernon Davis and Michael Crabtree, and Kendall Hunter ran for a 14-yard TD as San Francisco (7-2-1) scored on its first four possessions.

Aldon Smith had 5.5 of the six sacks of Jason Campbell, Jay Cutler's fill-in. Campbell threw a 13-yard touchdown pass to Brandon Marshall but was intercepted twice in his first start since 2011 for Oakland. Chicago fell to 7-3.

NFL suspends Ravens' Reed

The NFL suspended Ravens safety Ed Reed for Sunday's game against the Chargers for repeated hits to the head and neck area of defenseless players.

Reed is suspended for violating player safety rules three times in the past three seasons. The latest came in Sunday night's 13-10 win over the Steelers, when he was penalized for a hit to the head of receiver Emmanuel Sanders.

McGahee tears ligament

Broncos running back Willis McGahee tore a ligament in his right knee Sunday and is expected to miss the rest of the regular season. An MRI showed a "nonsurgical" tear, said coach John Fox, who added there was no immediate plan to put McGahee on injured reserve.

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Around the league

NFL.com reported the Steelers will start quarterback Charlie Batch against the Browns because Byron Leftwich suffered fractured ribs in the loss to the Ravens, his first start since 2009 . . . Redskins safety Brandon Meriweather (torn ACL) is out for the season . . . The Jaguars will start quarterback Chad Henne against the Titans.