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2004: ELI MANNING
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Drafted: 1st round, No. 1 overall by the San Diego Chargers
College: Mississippi (10,119 yards, 81 TDs in three-plus years)
NFL: Manning refused to play in San Diego, forced a trade to the Giants and beat the 18-0 Patriots in Super Bowl XLII in 2008. He then beat the Patriots in Super Bowl XLVI in 2012 as he grew into a truly elite quarterback. He has thrown 229 career TDs but has led the NFL in interceptions three times, too. In 2013, Manning threw for 3,818 yards, 18 TDs and a league-high 27 INTs.