Casey Cizikas and Travis Hamonic are done for the remainder of this Islanders season.

Hamonic suffered a left wrist/ hand injury in a first-period fight with Dale Weise during the Islanders’ 6-3 loss to the Flyers on Thursday night. Nothing is broken, but a source said Hamonic, who had a soft cast on his left wrist after Thursday night’s game, will not play again this season. Hamonic already missed 24 games with a knee injury before returning in early March.

Cizikas, who missed 11 games with a broken hand earlier this month, will not be back. According to sources, his hand still is causing problems and he might need surgery. He had a goal and an assist in six games since his return.

“It’s not looking too good for either of them,” Doug Weight said before Friday night’s game.

Shane Prince returned to the lineup in Cizikas’ spot. Thomas Hickey, a healthy scratch the past two games, took Hamonic’s spot on defense.

Cizikas and Hamonic were two of the feistier Islanders after the team fell behind 5-0 on Thursday night, with Cizikas going nose-to-nose with Flyers menace Radko Gudas at the second-period horn.

“There’s a way you need to play this time of year and we’ve been doing the opposite, and I don’t get it,” Weight said. “You get the puck in and go play with some bite. That’s it. I’m perplexed and it’s on me.”

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Elias retiring

Patrik Elias announced his retirement Friday after 20 seasons with the Devils. The franchise’s leader in goals, assists and points hadn’t played since early last season and did not have a contract this season while he mulled his decision.

Like many elite players of the last two decades, Elias, who won Stanley Cups in 2000 and 2003, was an Islander-killer. His 86 points in 91 games against the Isles were highs for him against any NHL team.

Elias will skate warmups with the Devils when the Isles visit Newark on April 8. His No. 26 will be retired sometime next season.