Nick Leddy, the Islanders' most durable defenseman this season, will miss at least two weeks with an upper-body injury. Leddy missed Tuesday's 2-1 loss to the Rangers with the injury, suffered in the second period of Monday's overtime win in Toronto, so it's yet another test of the team's depth as the regular season winds down.

"He was missed, of course, but we have guys who have been out of the lineup who are more than capable," said Johnny Boychuk, Leddy's defense partner. "He's missed, but I thought we did a good job."

Brian Strait rotated back into the lineup and the Islanders held the Rangers to just 22 shots on Jaroslav Halak and only a handful of scoring chances. Rick Nash's game-winner 2:50 into the third period was not one of them, with his toss from the blue line banking off Ryan Strome's skate and into the net.

Still, Leddy is a big loss, even for a relatively quiet stretch of time for the Islanders. They have only five games in the next 14 days, having already played a league-high 69 games.

The Isles have no plans to call up either Griffin Reinhart or Ryan Pulock from Bridgeport to get a shot at filling Leddy's spot, so Strait will remain. Jack Capuano juggled two of his defense pairs, putting Calvin de Haan with Boychuk and Strait with Travis Hamonic.

Leddy was playing his 320th consecutive game on Monday when he was sidelined. He cut down the slot on a scoring attempt late in the second period when he took a slash to his right side from the Leafs' Joffrey Lupul that had Leddy doubled over.

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He continued on with his shift and tried to reach out his right arm to knock Morgan Rielly off the puck, but Leddy immediately doubled over again, headed to the bench and missed the final period.

The Islanders were off on Wednesday and have consecutive home games against the Senators and Canadiens on Friday and Saturday.

Notes & quotes:Kael Mouillierat was sent back to Bridgeport on Monday. He had a goal and assist in six games with the Isles, the first NHL stint for the 27-year-old center.