A 40-year-old Medford woman was killed early Saturday in a three-car crash in Farmingville, police said.

Jennifer Colon was pronounced dead at the scene after her 2002 Chevrolet was struck by a pickup that had been struck by another car.

The crash happened shortly before 7 a.m. at Horseblock Road and Old Medford Avenue, police said.

Police said Joseph Pedro, 16, of Farmingville, was driving a 2013 Dodge Ram pickup east on Horseblock Road when he was struck by Franklyn Martinez, 23, of Central Islip, who was driving a 1996 Toyota. Martinez was traveling north on Old Medford Avenue, police said. Colon had been traveling west on Horseblock Road when Pedro struck her vehicle.

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Pedro and Martinez were transported to Stony Brook University Hospital and treated for non-life-threatening injuries.

All three vehicles were impounded for safety checks, and police said the investigation is continuing. Detectives are asking any witnesses to call the Sixth Squad at 631-854-8652.