A driver was killed and her two passengers injured in a two-car accident that closed at least three lanes of the Long Island Expressway for several hours during Wednesday's afternoon rush hour, Suffolk police said.

The crash on the eastbound lanes occurred in Hauppauge about 4:10 p.m. near Exit 57, Veterans Memorial Highway, when the driver of a sport utility vehicle veered across several lanes and crashed into another vehicle by the ramp, said Deputy Insp. Stan Grodski of the highway patrol unit.

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"It appeared she was trying to get to the ramp," he said of the SUV driver. "There are skid marks that go across all three lanes."

Fourth Squad detectives and crime scene officers gathered evidence Wednesday, police said. The LIE reopened about 7:30 p.m. Wednesday.

The two passengers in the SUV were taken to Stony Brook University Hospital, one with serious injuries, police said.

The other vehicle's driver, who was the sole occupant, was not injured, police said.