Eli Manning, QB, N.Y. Giants (at New England): Patriots allowing 323 passing yards per game.
Beanie Wells, RB, Arizona (vs. St. Louis): Rams are ranked last against run.
LeGarrette Blount, RB, Tampa Bay (at New Orleans): Saints give up league-high 5.5 yards per carry.
Brandon Lloyd, WR, St. Louis (at Arizona): Cardinals have allowed 100 yards to six different receivers.
A.J. Green, WR, Cincinnati (at Tennessee): Only New England has allowed more passing yards than Titans over past five weeks.
Jermaine Gresham, TE, Cincinnati (at Tennessee): Tennessee allows sixth-most fantasy points to tight ends.
Dallas defense (vs. Seattle): Seahawks' offense scores little and gives up plenty of sacks and turnovers.
Ryan Fitzpatrick, QB, Buffalo (vs. Jets): Gang Green has allowed league-low four TDs through air.
Chris Johnson, RB, Tennessee (vs. Cincinnati): He might be splitting carries with Javon Ringer. Bengals second vs. run.
DeMarco Murray, RB, Dallas (vs. Seattle): Seahawks yield just 3.2 yards per rush.
Anquan Boldin, WR, Baltimore (at Pittsburgh): Steelers haven't allowed more than 82 yards to a wide receiver.
Stevie Johnson, WR, Buffalo (vs. Jets): Jets are seventh against pass.
Heath Miller, TE, Pittsburgh (vs. Baltimore): Ravens allow just 26.4 yards per game to tight ends.
N.Y. Jets defense (at Buffalo): Bills are ranked fourth in scoring and give up second-fewest sacks.