Four people were shot at a bodega in Harlem Wednesday afternoon.

The victims, three men and a woman, were rushed to Harlem Hospital after cops responded to the scene at Madison Avenue and East 135th Street around 3:25 p.m., the FDNY said.

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One of the male victims was reported not likely to survive, according to a fire department spokesman.

There was no immediate information about suspects and the investigation is ongoing.

But neighbors say the area is no stranger to crime. 

"That corner is always hot with activity," said Ramona Reyes, who lives in the building above the bodega where the shooting happened. "They killed a guy like five years ago here and there's always something going on there."