Defenseman Brady Skjei will make his NHL debut for the Rangers Tuesday night against the Edmonton Oilers at Madison Square Garden.

Skjei, 21, the team’s No. 1 draft choice (28th overall) in 2012, is being summoned from the AHL’s Hartford Wolf Pack to step in for Dan Girardi, who is sitting out with knee swelling.

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Skjei (pronounced Shea), is a 6-3 Minnesota native who has two goals and nine assists in 27 games for the Wolf Pack this season.

Considered the team’s top defensive prospect, Skjei is a swift, smooth skater for his size, often compared to Ryan McDonagh, and is known as a shutdown blueliner.

According to coach Alain Vigneault, who spoke to the media after Tuesday morning’s skate, McDonagh, a lefty, will play the right side with Marc Staal Tuesday night. He has switched sides previously, most notably for Team USA in the last Winter Olympics.

Girardi is a righty, and Skjei a lefty; Vigneault said he would mix and match the second and third defensive pairs of Keith Yandle, Dylan McIlrath, Dan Boyle and Skjei during the game.