Ben Roethlisberger (Steelers, QB): Roethlisberger has requested going to the spread offense more and it worked last week. He has nine TDs and one INT the last three games. Look for more of the same against the Patriots, who rank last against the pass allowing an average of 322.2 yards per game.
Eli Manning (Giants, QB): After a slow start, Manning has played well the last five games. He is averaging 302 yards passing with 11 TDs and four INTs in that span. The Dolphins have just two interceptions and have allowed 12 passing TDs.
DeMarco Murray (Cowboys, RB): Murray broke out with 253 yards rushing on 25 carries last week, but it did come against the Rams, who rank last against the run. He gets another good matchup against the Eagles, who allow 4.8 yards per carry.
Darren Sproles (Saints, RB): Coach Sean Payton has done a phenomenal job utilizing Sproles. He is averaging 7.4 yards per carry and caught 45 passes for 329 yards with four total TDs. The Rams have allowed an average of 183.8 yards per game and 5.5 yards per carry.
Pierre Thomas (Saints, RB): Mark Ingram is out this week, so Thomas will get an increase in touches. The matchup against the Rams makes Thomas an excellent play.
Vincent Jackson (Chargers, WR): Jackson has battled through injuries and been shut down by Darrelle Revis and Champ Bailey the last two games. Jackson is a good buy low.
Antonio Brown (Steelers, WR): Brown had seven catches for 102 yards last week and the Patriots are last against the pass.
Emmanuel Sanders (Steelers, WR): Hines Ward might be out and Sanders would likely draw the start. He had five catches for 46 yards with a TD last week.
Torrey Smith (Ravens, WR): Can be boom or bust because of Joe Flacco's inconsistency. Smith does get several deep targets per game and the Cardinals rank 28th against the pass.
Fred Davis (Redskins, TE): The No. 1 passing target for the Redskins. He has 12 receptions for 175 yards with a TD the last two games.