Eugenie Bouchard attempts to cool down with bags of ice...

Eugenie Bouchard attempts to cool down with bags of ice and an ice towel around her neck between a game against Ekaterina Makarova during a women's singles match at the 2014 U.S. Open tennis tournament on Monday, Sept. 1, 2014. Credit: Kathleen Malone-Van Dyke

The heat got to Eugenie Bouchard on Monday before Ekaterina Makarova did.

The 20-year-old Canadian had to call a medical timeout after the fifth game of the second set. The WTA Tour's training staff attended to her, rubbing her down with ice and taking her blood pressure. Bouchard returned to the court, but she had a long, hot road to go and couldn't get to the end of it. Makarova prevailed, 7-6 (2), 6-4.

"I was feeling very light- headed and dizzy on the court," Bouchard said. "Just seeing things a little blurry."

It wasn't a new sensation for her. "I remember a few times as a junior in Australia," Bouchard said. "I have had a few late, tough matches here, and I don't think I was fully recovered from those."

Sitting on the other side of the umpire's chair was Makarova, who wasn't the least bit annoyed that Bouchard had called the timeout.

"Well, actually, I thought thanks, because I also was tired," Makarova said. "It was really help for me also because I had some time to recover and also to use some ice bags. It was actually kind of a good medical timeout."

The fourth-round loss ended a sensational Grand Slam season for Bouchard, cumulatively the best of any player. She lost in the final at Wimbledon to Petra Kvitova and reached the Australian Open and French Open semifinals.

Makarova will play Victoria Azarenka in the quarters. Azarenka defeated the pesky Aleksandra Krunic, 4-6, 6-4, 6-4.

Serena Williams continued her roll toward a third straight Open title with a 6-3, 6-3 win over Kaia Kanepi. While Kanepi was no pushover, the shot that gave Williams the most difficulty was a lob from Kanepi that the 17-time major champion whiffed on.

"I didn't want to hit it," Williams said. "I was like, these are the shots Venus usually takes in doubles. Where is Venus when you need her? You could tell I didn't want to hit it. Should I let it bounce? I was like, 'Let it bounce, let it bounce.' Pride got the best of me. I was like, 'Take it out of the air.' I don't think I even hit [it]."

Williams' next opponent is Flavia Pennetta, a 7-5, 6-2 winner over Casey Dellacqua. Both are 32, the oldest players remaining in the women's draw. Pennetta has not beaten Williams in five career meetings, and although she says she still believes she can beat the five-time Open champion, she can admit something else.

"She's better than me," said Pennetta, the No. 11 seed. "But if I still believe I can beat her, maybe if she doesn't have a good day, I can do that. If I get on the court and just play [not to lose] 6-0, 6-0, I [will lose] 6-0, 6-0."

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