Travel Most popular destinations for spring break March 18, 2010 2:48 PM Print Share fbShare Tweet Email The Top 10 spring break destinations booked this year, according to LastMinuteTravel.com: 1. Las Vegas 2. Orlando, Fla. 3. New York 4. Miami 5. San Diego 6. Chicago 7. San Francisco 8. Los Angeles 9. Cancun, Mexico 10. Boston Share on Facebook Share on Twitter Comments We're revamping our Comments section. Learn more and share your input.