Katherine Heigl rose to prominence as Dr. Izzy Stevens on "Grey's Anatomy," and moved on to become a rom-com queen. See photos of the actress from 2009-2016.

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Actress Katherine Heigl speaks on stage at the "Doubt" panel discussion during the CBS portion of the 2016 Television Critics Association Summer Tour at The Beverly Hilton Hotel on Aug. 10, 2016, in Beverly Hills, Calif.

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Actress Katherine Heigl arrives at the CBS, CW, Showtime Summer TCA Party at Pacific Design Center on Aug. 10, 2016, in West Hollywood, Calif.

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Actress Katherine Heigl cooks on stage during the Grand Tasting presented by ShopRite featuring Samsung culinary demonstrations presented by MasterCard at the Food Network & Cooking Channel New York City Wine & Food Festival presented by Food & Wine at Pier 94 on Oct. 17, 2015 in Manhattan.

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Actress Katherine Heigl attends Universal, NBC, Focus Features and E! Entertainment's 2015 Golden Globe Awards After Party sponsored by Chrysler and Hilton at The Beverly Hilton Hotel on Jan. 11, 2015, in Beverly Hills, Calif.

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Actress Katherine Heigl attends the 72nd Annual Golden Globe Awards at The Beverly Hilton Hotel on Jan. 11, 2015, in Beverly Hills, Calif.

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On top: Executive producers Bob Simonds, Rodney Faraon, Nancy Heigl. On bottom: Executive producer Ed Bernero, actors Katherine Heigl, Alfre Woodard and executive producer Joe Carnahan speak on stage at the "State of Affairs" panel during the NBCUniversal portion of the 2014 Summer Television Critics Association at The Beverly Hilton Hotel on July 13, 2014 in Beverly Hills, Calif.

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Actress Katherine Heigl attends NBCUniversal's 2014 Summer TCA Tour - Day 1 at The Beverly Hilton Hotel July 13, 2014 in Beverly Hills, Calif.

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Jessica Hart, Jena Malone and Katherine Heigl attend the J. Mendel Fall 2013 fashion show during Mercedes-Benz Fashion Week at The Theatre at Lincoln Center on Feb. 13, 2013, in Manhattan.

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Actress Katherine Heigl attends the Fall 2013 fashion show during Mercedes-Benz Fashion Week at The Stage at Lincoln Center on Feb. 11, 2013.

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Actress Katherine Heigl speaks on stage at the 40th AFI Life Achievement Award honoring Shirley MacLaine at Sony Pictures Studios on June 7, 2012, in Culver City, Calif.

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Katherine Heigl and Josh Kelley attend the Paris premiere of "One For The Money" at Cinema Gaumont Marignan on Jan. 31, 2012, in Paris, France.

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Presenters Katherine Heigl and Josh Kelley speak on stage at the 2011 American Music Awards held at Nokia Theatre L.A. Live on Nov. 20, 2011, in Los Angeles, Calif.

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Actors Katherine Heigl and Sofia Vergara pose at the after party for the premiere of Warner Bros. Pictures' "New Year's Eve" at Hollywood and Highland on Dec. 5, 2011, in Los Angeles, Calif.

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Actress Katherine Heigl attends the "Life As We Know It" premiere at the Ziegfeld Theatre in Manhattan on Sept. 30, 2010.

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Actress Katherine Heigl wins the Female Star of the Year Award at the ShoWest Final Night Talent Awards in Las Vegas on March 18, 2010.

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Actress Katherine Heigl attends the 13th annual ASPCA Bergh Ball at The Plaza Hotel in Manhattan on April 15, 2010.

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Actress Katherine Heigl poses at the after party for the premiere of Columbia Pictures' "The Ugly Truth" at Boulevard3 in Los Angeles, Calif., on July 16, 2009.

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Actress Katherine Heigl arrives for the European premiere of the film, "The Ugly Truth" at Leicester Square, London, on Aug. 4, 2009.

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