"The Other Guys" are the main guys at the box office, knocking off "Inception" to take the No. 1 spot.

The buddy-cop parody starring Will Ferrell and Mark Wahlberg made $35.6 million in its opening weekend, The Associated Press reports.

It's the second-highest debut for a film in which Ferrell has starred, and yet another strong showing for the movies he's made with his frequent collaborator, writer-director Adam McKay. Their biggest opening was "Talladega Nights: The Ballad of Ricky Bobby," which debuted at No. 1 with $47 million in August 2006.

"Inception," which had been the top film in the country the past three weeks, fell to No. 2 with $18.6 million.

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