Here are some notable trades around the majors.
The Braves acquired outfielder Rick Ankiel and right-handed reliever Kyle Farnsworth from the Royals in exchange for outfielder Gregor Blanco, right-handed reliever Jesse Chavez and left-handed reliever Tim Collins.
The Dodgers acquired left-handed starting pitcher Ted Lilly, infielder Ryan Theriot and $2.5 million from the Cubs on for second baseman Blake DeWitt and Minor Leaguers Kyle Smit and Brett Wallach.
The Dodgers traded right-hander James McDonald and minor-league outfielder Andrew Lambo to the Pirates for Octavio Dotel.
A three-way deal between the Padres, Indians and Cardinals has been completed, with Ryan Ludwick moving from St. Louis to San Diego and Jake Westbrook going to the Redbirds.
The Pirates are sending Bobby Crosby, Ryan Church and D.J. Carrasco to Arizona as part of a trade to acquire catcher Chris Snyder and a Minor League player.
The Rangers traded catcher Jarrod Saltalamacchia to the Red Sox for right-handed pitcher Roman Mendez, first baseman Chris McGuiness, a player to be named and cash considerations.
The Red Sox traded Ramon Ramirez to the Giants for right-handed pitcher Daniel Turpen.
The Marlins traded right-hander Rick VandenHurk to the Orioles for Will Ohman.
The Giants traded right-hander Joe Martinez to the Pirates for left-hander Javier Lopez.
The Rays acquired right-handed relief pitcher Chad Qualls from the Arizona Diamondbacks in exchange for a player to be named later.
The Nationals traded infielder Cristian Guzman to the Rangers for pitching prospects Ryan Tatusko and Tanner Roark.
The White Sox acquired starting pitcher Edwin Jackson from the D-backs for right-hander Daniel Hudson and left-hander David Holmberg.
The Twins completed a trade with the Nationals on Thursday, acquiring Matt Capps in exchange for catching prospect Wilson Ramos.
The Padres acquired third baseman Miguel Tejada from the Orioles in exchange for minor league pitcher Wynn Pelzer.
The Astros traded Roy Oswalt to Phillies for lefty J.A. Happ, minor league shortstop Jonathan Villar and minor league outfielder Anthony Gose, who was then flipped to the Blue Jays for first-base prospect Brett Wallace.
The Dodgers acquired Scott Podsednik from the Royals for minor leaguer catcher Lucas May and pitcher Elisaul Pimentel.
In the wake of injuries to Brandon Inge, Magglio Ordonez and Carlos Guillen, the Tigers acquired third baseman Jhonny Peralta and cash on Wednesday from the Indians for minor-league pitcher Giovanni Soto.