Isaiah Crowell of the New York Jets runs the ball...

Isaiah Crowell of the New York Jets runs the ball against the Buffalo Bills at MetLife Stadium on Nov. 11, 2018. Credit: Jim McIsaac

FLORHAM PARK, N.J. — The Jets will be without their top running back and leading receiver when they face the Texans on Saturday at MetLife Stadium.

Isaiah Crowell (toe) and Quincy Enunwa (ankle), both of whom were injured in Sunday’s win over the Bills, have been ruled out. It’s the first game Crowell will miss in his NFL career. He had played in 77 straight.

The Jets are banged up in the backfield. Elijah McGuire, who ran for the game-winning touchdown in Buffalo, was limited Thursday with an ankle issue and will be a game-time decision. Rookie Trenton Cannon (toe) was a full participant Thursday for the first time this week.

McGuire, who missed the first eight games with a broken foot, has 158 yards rushing on 42 carries and 11 catches for 90 yards. Cannon has rushed for 80 yards on 27 carries and caught 13 passes for 115 yards.

“It’s a good opportunity,” coach Todd Bowles said of the young running backs. “You like what you see, so they get a chance to prove themselves.”

Enunwa leads the Jets with 38 receptions for 449 yards, although he has scored only one touchdown. He missed two games earlier this season with an ankle issue; his current injury is to the other ankle.

Robby Anderson and Jermaine Kearse will remain top targets for Sam Darnold, and Rishard Matthews and Andre Roberts could see bigger roles against the Texans.

Linebacker Jeremiah Attaochu also will not play because of a concussion.

Three other members of the Jets’ defense will be game-time decisions, according to Bowles.

Cornerback Trumaine Johnson was limited Thursday with a sore foot. It was the first time this week he didn’t practice in full. Outside linebacker Jordan Jenkins was limited because of an ankle injury he suffered on a chop block from Buffalo’s Dion Dawkins. Linebacker and special teams player Kevin Pierre-Louis (shoulder) also was limited.

Notes & quotes: Bowles said there is no plan at this time to make Davis Webb the No. 2 quarterback on game day. If healthy, Sam Darnold and Josh McCown will remain ahead of Webb. “He gets plenty of practice reps,” Bowles said.

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