Albert Kligman, dermatologist discovered Retin-A, dies
By his experiments involving prisoners, has died. He was 93.. Kligman died Feb. 9 of heart failure at Pennsylvania Hospital, his daughter Gail Kligman, a sociology professor at the University of California, Los Angeles, said yesterday.. Kligman is credited as being the first dermatologist to show a link between sun exposure and wrinkles. He coined the term "photoaging" to describe skin aging caused by the sun.. In 1967, he patented Retin-A, a vitamin A derivative known generically as tretinoin, as an acne treatment and received a new patent in 1986 after discovering its wrinkle-fighting ability.. As the architect of Holmesburg Prison's experimental research program from 1951 to 1974, Kligman directed and performed hundreds of experiments on prisoners. The experiments included testing of mind-altering agents, dioxin and "skin-hardeners" to protect skin from toxic chemicals. Many were performed under contracts with pharmaceutical and chemical companies, cosmetics firms, federal agencies and the military. At the time, prison experiments were common.. Medical testing at Holmesburg took place until 1974, when it was banned by the city amid congressional hearings into medical experimentation, including Tuskegee University tests that infected black men with syphilis.. Kligman never wavered in his defense of the experiments, insisting that the test subjects did not suffer any long-term harm and maintaining that the research should not have been halted because of the scientific advances it might have yielded.. "The whole thing is so preposterous," he said in a 2003 interview in Dermatology Times. "It gets brought up every few years and the explanations have to start all over again."
NewsdayTV's Doug Geed visits two wineries and a fish market, and then it's time for holiday cheer, with a visit to a bakery and poinsettia greenhouses.
Credit: Randee Dadonna
Out East with Doug Geed: Wine harvests, a fish market, baked treats and poinsettias NewsdayTV's Doug Geed visits two wineries and a fish market, and then it's time for holiday cheer, with a visit to a bakery and poinsettia greenhouses.
NewsdayTV's Doug Geed visits two wineries and a fish market, and then it's time for holiday cheer, with a visit to a bakery and poinsettia greenhouses.
Credit: Randee Dadonna
Out East with Doug Geed: Wine harvests, a fish market, baked treats and poinsettias NewsdayTV's Doug Geed visits two wineries and a fish market, and then it's time for holiday cheer, with a visit to a bakery and poinsettia greenhouses.
