Peyton Manning watches the action during the game against the...

Peyton Manning watches the action during the game against the Washington Redskins at Lucas Oil Stadium. (Aug. 19, 2011) Credit: Getty Images

INDIANAPOLIS -- Peyton Manning underwent more neck surgery Thursday, the third time in 19 months, and will miss not only the opening game but possibly the entire season.

Losing Manning for any stretch of time is a huge blow to the Colts. The four-time NFL MVP hasn't missed a game in 14 NFL seasons, with 227 consecutive starts.

"Rehabilitation from such surgery is typically an involved process," the team said in a statement, calling the procedure "uneventful." "Therefore, there will be no estimation of a return date at this time. We will keep Peyton on the active roster until we have a clear picture of his recovery process."

-- AP

Suffolk County Sheriff Errol Toulon Jr. spoke with NewsdayTV's Ken Buffa about what life is like for the Gilgo Beach serial killer Rex Heuermann in jail. Credit: Anthony Florio; File Footage; Photo Credit: Newsday / James Carbone, John Paraskevas; AP / David Bookstaver, Clark County Sheriff's Office, Richard Drew, Mitchell Tapper, Don Ryan; Peconic River Sportsman’s Club / Kerry Goldberg

'He will be ... coming out of prison in a body bag' Suffolk County Sheriff Errol Toulon Jr. spoke with NewsdayTV's Ken Buffa about what life is like for the Gilgo Beach serial killer Rex Heuermann in jail.

Suffolk County Sheriff Errol Toulon Jr. spoke with NewsdayTV's Ken Buffa about what life is like for the Gilgo Beach serial killer Rex Heuermann in jail. Credit: Anthony Florio; File Footage; Photo Credit: Newsday / James Carbone, John Paraskevas; AP / David Bookstaver, Clark County Sheriff's Office, Richard Drew, Mitchell Tapper, Don Ryan; Peconic River Sportsman’s Club / Kerry Goldberg

'He will be ... coming out of prison in a body bag' Suffolk County Sheriff Errol Toulon Jr. spoke with NewsdayTV's Ken Buffa about what life is like for the Gilgo Beach serial killer Rex Heuermann in jail.

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