Opening-season road trips don't seem to agree with the Boston Red Sox.

A year after losing their first six games to start the season, the Red Sox finished a 1-5 road trip with a 3-1 loss to the Toronto Blue Jays yesterday.

"That's not the road trip we want," Boston manager Bobby Valentine said, "but we've got a homestand coming up and we'll try to see if we can't get things going in the right direction."

Ricky Romero (1-0) outdueled Jon Lester and Yunel Escobar drove in two runs for the Blue Jays, who took two of three games from Boston.

Rays 4, Tigers 2: Ben Zobrist hit a tiebreaking, two-run single in the ninth inning, and visiting Tampa Bay scored four runs in its final at-bat to beat Justin Verlander. The Tigers (4-1) lost for the first time this season.

Verlander (0-1) took a one-hitter into the ninth and hadn't allowed a run all season, but he gave up one on a wild pitch.

White Sox 10, Indians 6: A.J. Pierzynski hit a three-run homer and drove in four runs to lead visiting Chicago. The White Sox scored four runs in the first off Justin Masterson (0-1), but Cleveland closed to 5-4 in the fifth against John Danks (1-1) on Travis Hafner's two-run double.

Mariners 4, Rangers 3: John Jaso had an RBI single with two outs in the ninth to cap a three-run rally off new Rangers closer Joe Nathan (0-2) for visiting Seattle.

Twins 6, Angels 5: Jamey Carroll had his first two hits with host Minnesota, including the go-ahead single in the seventh, and Josh Willingham hit a two-run homer.

Phillies 7, Marlins 1: Roy Halladay (2-0) threw seven sharp innings and host Philadelphia broke out of their offensive slump, beating the Marlins in their first game without suspended Ozzie Guillen. The manager was suspended five games by the Marlins on Tuesday for saying he admired Cuban dictator Fidel Castro.

Braves 6, Astros 3:Jason Heyward homered and drove in two runs and David Ross hit a two-run double in his 2012 debut and for visiting Atlanta.

Reds 4, Cardinals 3: Joey Votto tied a career best with four hits and scored the go-ahead run on pinch hitter Chris Heisey's ninth-inning single for host Cincinnati.

Brewers 2, Cubs 1: George Kottaras hit a two-run homer in the seventh inning and Yovani Gallardo (1-1) bested Ryan Dempster (0-1) for visiting Milwaukee. -- AP

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