Houston defensive back Jordan Allen (6) celebrates after breaking up...

Houston defensive back Jordan Allen (6) celebrates after breaking up a pass in the end zone with Kentrell Webb during the first half of an NCAA college football game against Oklahoma State, Saturday, Oct. 17, 2026, in Houston. Credit: AP/Eric Christian Smith

HOUSTON — Conner Weigman threw for 343 yards and tied a career high with five touchdown passes to help No. 20 Houston beat No. 18 Oklahoma State 35-32 on Saturday night for its fourth straight victory.

Weigman finished 24 of 33 and rushed for 52 yards. He threw touchdown passes of 2, 7, 2, 21 and 48 yards and Houston (6-1, 3-1 Big 12) had 505 yards.

Amare Thomas caught seven passes for 126 yards and two touchdowns, and Trent Walker had seven receptions for 104 yards and a touchdown. Patrick Overmyer and Koby Young also caught touchdown passes.

Drew Mestemaker was 22 of 34 for 365 yards and three touchdowns for Oklahoma State (4-2, 2-1). Caleb Hawkins rushed 68 yards and caught seven passes for 125 yards and a touchdown. Wyatt Young had five catches for 99 yards and a touchdown and Justin Bowick had a touchdown catch. The Cowboys had 499 yards.

After the Cowboys closed within three on Bowick’s 8-yard touchdown catch with 4:54 remaining, Houston was able to run out the clock as Walker caught an 18-yard reception from Weigman on third-and-7 with 2 1/2 minutes left, and Weigman rushed for a first down with two minutes left to ice the win.

The takeaway

Oklahoma State: The Cowboys will likely fall a couple spots in the AP poll following the loss. … Oklahoma State is still in the hunt in the Big 12 but will need help following its first Big 12 loss.

Houston: The Cougars will likely jump in the AP poll after their first win over a ranked team this season. … Houston remains in the hunt in the Big 12 race, with Utah looming on the schedule.

Houston wide receiver Amare Thomas (0) catches a pass for...

Houston wide receiver Amare Thomas (0) catches a pass for a touchdown as Oklahoma State safeties Christian Bodnar (6) and Quinton Hammonds (7) defend during the first half of an NCAA college football game Saturday, Oct. 17, 2026, in Houston. Credit: AP/Eric Christian Smith

Up next

Oklahoma State: Hosts Colorado on Saturday.

Houston: At No. 11 Utah on Saturday.

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