Drew Brees completed 31 of 35 passes for 325 yards and five touchdowns as the host New Orleans Saints (4-2) set a franchise record for points and victory margin in a 62-7 demolition of the Indianapolis Colts (0-7) Sunday night.

Saints coach Sean Payton watched the game up in the coaches' booth, where he could sit comfortably with his broken left leg propped up. Brees had two touchdown passes to Marques Colston and one to Darren Sproles in the first quarter. His fourth and fifth touchdown tosses went to tight end Jimmy Graham in the third quarter.

Texans 41, Titans 7

Arian Foster ran for 115 yards and two touchdowns and added 119 more receiving with a 78-yard TD as Houston moved back into first place in the AFC South. The Texans (4-3) snapped a two-game skid. Matt Schaub threw for 296 yards and two TDs. Tennessee (3-3) has lost two straight.

Packers 33, Vikings 27

Aaron Rodgers kept visiting Green Bay (7-0) unbeaten with three TDs and 335 yards passing, holding off Minnesota in rookie Christian Ponder's first start. Adrian Peterson rushed for 175 yards and a TD on 24 carries for the Vikings (1-6). Ponder threw for 219 yards, two TDs and two interceptions.

Cowboys 34, Rams 7

DeMarco Murray ran for a franchise-record 253 yards, including a 91-yard touchdown run that's the second-longest in club history, to lead host Dallas (3-3). The Rams (0-6) were without quarterback Sam Bradford.

Bears 24, Bucs 18

Matt Forte ran for 145 yards and a touchdown and Chicago held on at England's Wembley Stadium. Jay Cutler threw for 226 yards and a touchdown and the Bears (4-3) intercepted Josh Freeman four times. The Buccaneers (4-3) lost for the second time in three years in London.

Falcons 23, Lions 16

Matt Ryan ran and threw for touchdowns to give Atlanta a double-digit lead in the first half, and the visiting Falcons (4-3) held on for the win. Calvin Johnson caught his 10th touchdown pass of the season late in the third quarter to pull Detroit (5-2) within four points.

Steelers 32, Cardinals 20

Ben Roethlisberger threw 95 yards to Mike Wallace for the longest pass play in Steelers history as visiting Pittsburgh (5-2) beat Arizona (1-5). Roethlisberger, 25-for-38 for 340 yards, also had TD passes of 12 yards to Heath Miller and 4 yards to Emmanuel Sanders.

Panthers 33, Redskins 20

Cam Newton ran for a touchdown and threw for one in the second half for host Carolina (2-5). Jonathan Stewart added a touchdown run. Newton threw for 256 yards and ran for 59 more. He ran for his seventh touchdown on a 16-yard keeper. The Redskins are 3-3.

Chiefs 28, Raiders 0

Kendrick Lewis and Brandon Flowers returned interceptions for touchdowns and visiting Kansas City (3-3) took advantage of rusty quarterback play from Kyle Boller and Carson Palmer. The Raiders are 4-3.

Browns 6, Seahawks 3

Phil Dawson converted two field goals over 50 yards and had two others blocked, but it was enough for host Cleveland (3-3). Seattle (2-4) came in missing starting quarterback Tarvaris Jackson and lost running back Marshawn Lynch to a back injury during warmups.

-- AP

SUBSCRIBE

Unlimited Digital AccessOnly 25¢for 6 months

ACT NOWSALE ENDS SOON | CANCEL ANYTIME