Venus Williams with the backhand return of a serve by...

Venus Williams with the backhand return of a serve by Vesna Dolonts of Russia in their first round match. (Aug. 29, 2011) Credit: Joseph D. Sullivan

Venus Williams withdrew from the U.S. Open on Wednesday, the tournament announced.

The two-time Open champion cited an unspecified illness before her second-round matched scheduled for Wednesday afternoon against Sabine Lisicki.

Williams, 31, beat Vesna Dolonts, 6-4, 6-3, in her first-round match on Monday.

Get Venus Williams updates here.

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