STANFORD, Calif. -- LaMichael James ran for 146 yards and three touchdowns and No. 7 Oregon sprinted past third-ranked Stanford, 53-30, last night, giving Andrew Luck's Heisman Trophy campaign a blemish and taking a giant step toward hosting the inaugural Pac-12 championship.

James ran for scores from 1, 4 and 58 yards and had Stanford (9-1, 7-1) defenders slipping all over a slick field. The Ducks (9-1, 7-0) ended the nation's best winning streak at 17 games -- which the Cardinal began after a loss in Eugene more than a year ago -- and can clinch the league's North Division crown over Stanford with a win in one of their final two games.

Luck threw for 271 yards and three touchdowns with two interceptions and a fumble. Stanford had five total turnovers.

The Quack Attack just has Luck's number.

Oregon's no-huddle, spread-option ended any hopes of Stanford's first national championship. Instead, the Ducks are suddenly back in the BCS title mix after rolling off their ninth straight victory -- and first against a top-five team on the road team -- since a season-opening loss against top-ranked LSU.

Darron Thomas threw for 155 yards and three touchdowns to anchor one big-play burst after another. He tossed scores of 59 yards to Josh Huff and 41 yards to De'Anthony Thomas to leave sold-out Stanford Stadium stunned and silent.

The Cardinal did little with the few mistakes Oregon made.

James muffed a punt that gave Stanford a chance at the Oregon 34. The Ducks quickly stifled Stanford again, and Eric Whitaker missed a 48-yard field goal badly right.

When the Cardinal got the ball back, Isaac Remington smashed Luck and forced the quarterback to fumble. Oregon recovered and James followed with a 4-yard score on fourth-and-2 to give the Ducks a commanding 36-16 lead in the third quarter.

All the Luck in the world couldn't bring Stanford back.

The two offenses traded scores until Boseko Lokombo intercepted a pass by Luck and returned it 40 yards for a touchdown to give the Ducks a 53-30 lead.

Dewitt Stuckey also intercepted a pass by Luck that set up the Ducks' first score, a 4-yard touchdown pass from Darron Thomas to Lavasier Tuinei that started an avalanche of Oregon offense.

James ran through the middle untouched for a 58-yard touchdown to extend Oregon's lead to 15-6 early in the second quarter. The Ducks threatened to pad their lead again until Delano Howell, with a cast around his right hand, punched the ball loose from Kenjon Barner and Stanford recovered. -- AP

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