Johnny Depp attends the "The Rum Diary" New York premiere...

Johnny Depp attends the "The Rum Diary" New York premiere at the Museum of Modern Art. (Oct. 25, 2011) Credit: Getty Images

Johnny Depp has a new duet partner.

While rumors of the actor's possible split from longtime girlfriend French singer Vanessa Paradis swirl in the tabloids, word arrived Tuesday that he will sing with his pal shock rocker Marilyn Manson on his upcoming "Born Villain" album.

The duo, who have been friends since Manson's song "The Nobodies" was used in Depp's 2001 film "From Hell," will tackle the Carly Simon classic "You're So Vain." (Though "Born Villain" doesn't arrive in stores until May 1, fans on Long Island may get a sneak preview of the song when Manson plays The Paramount in Huntington on April 29.)

While Depp hasn't done much singing in public, his love of music is certainly no secret. A onetime owner of the famed Los Angeles club The Viper Room, Depp jammed on guitar with Keith Richards at the after-party for his movie "The Rum Diary" at Hiro Ballroom in October, days after joining ZZ Top on stage.

Depp's duet with Manson is a way to spark interest in the Ohio native's new album, the "Antichrist Superstar's" first since 2009's "The High End of Low" and the first release on his own label Hell, Etc.

"You're So Vain" won't be the album's first single, however. Manson has already picked "No Reflection" to kick off his comeback campaign. Of course, that won't stop all the bets on who Depp and Manson might be addressing with the kiss-off song.

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